Research at the Ravid laboratory covers the disciplines of biochemistry, cell biology, and genetics, taking advantage of the many research benefits offered by the Baker's yeast Saccharomyces cerevisiae as a model organism.

Our area of interest is protein quality control, a universal protective cellular mechanism for ensuring that damaged or aberrant proteins are recognized, repaired, or eliminated. Specifically, we are interested in understanding the role of ubiquitin-proteasome degradation systems in Quality Control-Associated Proteolysis (QCAP), and the outcome of their deterioration during aging. Our research is driven by findings that link defective ubiquitin conjugation or proteasome function and the concomitant accumulation of cellular protein aggregates, with many human neurodegenerative diseases.